It is called the double-strand-break model. New features in this model (contrasting with the Holliday model) are initiation at double-strand breaks, nuclease digestion of the aggressor …

A double-strand break repair model refers to the various models of pathways that cells undertake to repair double-strand breaks (DSB). DSB repair is an important cellular process, as the …

Model for repair of DNA double-strand breaks by homologous recombination in somatic cells. When a DNA double-strand break (DSB) occurs in a DNA molecule, repair can proceed by …

Jun 14, 2025 · Explore the double-strand break repair (DSBR) model of homologous recombination, including DSB initiation, 3′-end resection, strand invasion, branch migration, …

The Holliday model described some of the basic steps of the recombination process, but was unable to explain all sets of available genetic data. This was later achieved by a model …

Study with Quizlet and memorize flashcards containing terms like what is the first step in the double strand break model?, what protein causes the formation of a double strand break? …

In this review, we highlight the chief sources of DSBs and crucial requirements for each of these repair processes, as well as the methods to identify and study intermediate steps in DSB …

Double-strand DNA breaks are common events in eukaryotic cells, and there are two major pathways for repairing them: homologous recombination and nonhomologous DNA end joining …

Outline the stepwise process of homologous recombination, including double-strand break (DSB) recognition, 5′ end resection, and generation of 3′ single-stranded DNA overhangs.

A) The double-strand break repair model. Resection of ssDNA generates single-stranded 3’tails that can invade a homologous double-stranded DNA, forming a D-loop (displacement loop).