For direct reversal of alkylation events, a DNA methyltransferase or DNA glycosylase detects and removes the alkyl group. Excision repair can be specific or nonspecific. In base excision …

Deficiencies in DNA repair enzymes are occasionally caused by a newly arising somatic mutation in a DNA repair gene, but are much more frequently caused by epigenetic alterations that …

DNA Polymerases Lambda (λ) and Mu (μ) are members of the X-Family, and are primarily involved in DNA repair. Both polymerases function in repair of DNA double strand breaks …

Jul 30, 2025 · DNA repair enzymes are enzymes that recognize and correct physical damage in DNA, caused by exposure to radiation, UV light or reactive oxygen species. The correction of …

It can enlist the aid of enzymes involved in both base-excision repair (BER) and nucleotide-excision repair (NER) as well as using enzymes specialized for this function.

Oct 22, 2025 · Learn how DNA modifications can serve as a springboard to develop molecular workflows, using our enzyme recommendations and resources.

Jan 24, 2024 · The review addresses key questions, including the major types of DNA damage, common DNA repair mechanisms, the availability of reliable databases for DNA damage and …